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| Acceso al texto completo restringido a Biblioteca INIA Las Brujas. Por información adicional contacte bibliolb@inia.org.uy. |
Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
Fecha : |
18/12/2017 |
Actualizado : |
15/10/2019 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Autor : |
LOURENCO, D.A.L.; FRAGOMENI, B.O.; BRADFORD, H.L.; MENEZES I.R.; FERRAZ, J.B.S.; AGUILAR, I.; MISZTAL, I. |
Afiliación : |
D.A.L. LOURENCO, Universidad de Georgia (UG); B.O. FRAGOMENI, Universidad de Georgia (UG); H.L. BRADFORD, Universidad de Georgia (UG); I.R. MENEZES, FZEA, University of Sao Paulo.; J.B.S. FERRAZ, FZEA, University of Sao Paulo.; IGNACIO AGUILAR GARCIA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; I. MISZTAL, Universidad de Georgia (UG). |
Título : |
Implications of SNP weighting on single-step genomic predictions for different reference population sizes. |
Fecha de publicación : |
2017 |
Fuente / Imprenta : |
Journal of Animal Breeding and Genetics, 2017, v. 134 (6), p. 463-471. |
DOI : |
10.1111/jbg.12288 |
Idioma : |
Inglés |
Notas : |
Article history: Received: 28 February 2017 / Accepted: 19 July 2017.
This study was partially funded by the American Angus Association (St. Joseph, MO), Zoetis (Kalamazoo, MI) and by Agriculture and Food Research Initiative Competitive Grants no. 2015-67015-22936 from the US Department of Agriculture's National Institute of Food and Agriculture. We gratefully acknowledge the very helpful comments by the two anonymous reviewers, and we thank Andra H. Nelson for assisting with data analysis. |
Contenido : |
ABSTRACT.
We investigated the importance of SNP weighting in populations with 2,000 to 25,000 genotyped animals. Populations were simulated with two effective sizes (20 or 100) and three numbers of QTL (10, 50 or 500). Pedigree information was available for six generations; phenotypes were recorded for the four middle generations. Animals from the last three generations were genotyped for 45,000 SNP. Single-step genomic BLUP (ssGBLUP) and weighted ssGBLUP (WssGBLUP) were used to estimate genomic EBV using a genomic relationship matrix (G). The WssGBLUP performed better in small genotyped populations; however, any advantage for WssGBLUP was reduced or eliminated when more animals were genotyped. WssGBLUP had greater resolution for genome-wide association (GWA) as did increasing the number of genotyped animals. For few QTL, accuracy was greater for WssGBLUP than ssGBLUP; however, for many QTL, accuracy was the same for both methods. The largest genotyped set was used to assess the dimensionality of genomic information (number of effective SNP). The number of effective SNP was considerably less in weighted G than in unweighted G. Once the number of independent SNP is well represented in the genotyped population, the impact of SNP weighting becomes less important.
© 2017 Blackwell Verlag GmbH |
Palabras claves : |
ACCURAY; BAYES B; SNP WEIGHTING; VARIABLE SELECTION; WEIGTED SSGBLUP. |
Asunto categoría : |
-- |
Marc : |
LEADER 02612naa a2200277 a 4500 001 1057902 005 2019-10-15 008 2017 bl uuuu u00u1 u #d 024 7 $a10.1111/jbg.12288$2DOI 100 1 $aLOURENCO, D.A.L. 245 $aImplications of SNP weighting on single-step genomic predictions for different reference population sizes.$h[electronic resource] 260 $c2017 500 $aArticle history: Received: 28 February 2017 / Accepted: 19 July 2017. This study was partially funded by the American Angus Association (St. Joseph, MO), Zoetis (Kalamazoo, MI) and by Agriculture and Food Research Initiative Competitive Grants no. 2015-67015-22936 from the US Department of Agriculture's National Institute of Food and Agriculture. We gratefully acknowledge the very helpful comments by the two anonymous reviewers, and we thank Andra H. Nelson for assisting with data analysis. 520 $aABSTRACT. We investigated the importance of SNP weighting in populations with 2,000 to 25,000 genotyped animals. Populations were simulated with two effective sizes (20 or 100) and three numbers of QTL (10, 50 or 500). Pedigree information was available for six generations; phenotypes were recorded for the four middle generations. Animals from the last three generations were genotyped for 45,000 SNP. Single-step genomic BLUP (ssGBLUP) and weighted ssGBLUP (WssGBLUP) were used to estimate genomic EBV using a genomic relationship matrix (G). The WssGBLUP performed better in small genotyped populations; however, any advantage for WssGBLUP was reduced or eliminated when more animals were genotyped. WssGBLUP had greater resolution for genome-wide association (GWA) as did increasing the number of genotyped animals. For few QTL, accuracy was greater for WssGBLUP than ssGBLUP; however, for many QTL, accuracy was the same for both methods. The largest genotyped set was used to assess the dimensionality of genomic information (number of effective SNP). The number of effective SNP was considerably less in weighted G than in unweighted G. Once the number of independent SNP is well represented in the genotyped population, the impact of SNP weighting becomes less important. © 2017 Blackwell Verlag GmbH 653 $aACCURAY 653 $aBAYES B 653 $aSNP WEIGHTING 653 $aVARIABLE SELECTION 653 $aWEIGTED SSGBLUP 700 1 $aFRAGOMENI, B.O. 700 1 $aBRADFORD, H.L. 700 1 $aMENEZES I.R. 700 1 $aFERRAZ, J.B.S. 700 1 $aAGUILAR, I. 700 1 $aMISZTAL, I. 773 $tJournal of Animal Breeding and Genetics, 2017$gv. 134 (6), p. 463-471.
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INIA Las Brujas (LB) |
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Registro completo
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Biblioteca (s) : |
INIA La Estanzuela; INIA Las Brujas; INIA Tacuarembó; INIA Treinta y Tres. |
Fecha actual : |
01/02/2019 |
Actualizado : |
02/08/2021 |
Tipo de producción científica : |
Capítulo en Libro Técnico-Científico |
Autor : |
QUINCKE, A.; CUADRO, R.; GIORELLO, D.; BERMÚDEZ, R. |
Afiliación : |
JUAN ANDRES QUINCKE WALDEN, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; WASHINGTON ROBIN CUADRO LOPEZ, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; DIEGO GERMAN GIORELLO LEITES, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; RAÚL ENRIQUE BERMÚDEZ COQUARD, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
Título : |
Eficiencia relativa de la fertilización con fosforita natural respecto a superfosfato. |
Fecha de publicación : |
2019 |
Fuente / Imprenta : |
In: Quincke, A.; Cuadro, R. (Eds.). Fertilización de pasturas de leguminosas: resultados para el manejo del fósforo y el azufre. Montevideo (UY): INIA, 2019. |
Páginas : |
p. 33-37. |
Serie : |
(INIA Serie Técnica; 248) |
ISBN : |
978-9974-38-416-3 |
ISSN : |
1688-9266 |
DOI : |
http://doi.org/10.35676/INIA/ST.248 |
Idioma : |
Español |
Contenido : |
La fosforita natural (FN) o roca fosfórica es la materia prima que la industria utiliza en la producción de las fuentes solubles, por lo que u precio es menor que el de los fertilizantes solubles. |
Palabras claves : |
FOSFORITA NATURAL (FN); PASTURE; ROCA FOSFÓRICA. |
Asunto categoría : |
F01 Cultivo |
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/12373/1/st-248-2019-p.33-37.pdf
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Marc : |
LEADER 01034naa a2200253 a 4500 001 1059466 005 2021-08-02 008 2019 bl uuuu u00u1 u #d 020 $a978-9974-38-416-3 022 $a1688-9266 024 7 $ahttp://doi.org/10.35676/INIA/ST.248$2DOI 100 1 $aQUINCKE, A. 245 $aEficiencia relativa de la fertilización con fosforita natural respecto a superfosfato. 260 $c2019 300 $ap. 33-37. 490 $a(INIA Serie Técnica; 248) 520 $aLa fosforita natural (FN) o roca fosfórica es la materia prima que la industria utiliza en la producción de las fuentes solubles, por lo que u precio es menor que el de los fertilizantes solubles. 653 $aFOSFORITA NATURAL (FN) 653 $aPASTURE 653 $aROCA FOSFÓRICA 700 1 $aCUADRO, R. 700 1 $aGIORELLO, D. 700 1 $aBERMÚDEZ, R. 773 $tIn: Quincke, A.; Cuadro, R. (Eds.). Fertilización de pasturas de leguminosas: resultados para el manejo del fósforo y el azufre. Montevideo (UY): INIA, 2019.
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